Tuberculosis is a first magnitude sanitary problem with several factor
s that make difficult its eradication, among these are particularly im
portant those derived from the antituberculous therapy: noncompliance
and adverse reactions to the drugs used. We have developed a follow-up
program for ambulatory patients with antituberculous therapy that inc
ludes compliance control and systematical survey or possible adverse r
eactions. We expose our results after its application to 39 patients w
ith tuberculosis and 24 with tuberculous infection. The compliance lev
el among patients with tuberculous disease was 100% and among those wh
o were receiving chemoprophylaxis 75%, both values much higher than th
ose found in the literature. We detected adverse reactions in 43.6% of
the patients with tuberculous treatment and 37.5% of those receiving
chemoprophylaxis with isoniazid. Setting up follow-up programs in anti
tuberculous treatments notably helps to improve the compliance and the
safety of treatment