A. Tapiz et al., SKIN AFFECTATION AS UNIQUE MANIFESTATION OF CRYPTOCOCCOSIS, IN A PATIENT WITH AIDS, Revista Clinica Espanola, 194(9), 1994, pp. 689-691
We report an exclusively cutaneous case of cryptococcosis, which is ex
ceptional. He was a 33 years old patient with the acquired immunodefic
iency syndrome who presented with an ulcer-necrotic lesion at the nasa
l wings with a long and torpid evolution. Finally, culture and biopsy
were diagnostic of cryptococcosis. We ruled out affection of other org
ans and the cryptococcal antigen was negative in serum and cerebrospin
al fluid. The patient was treated with fluconazole and had a good clin
ical course. Its emphasized the scarcity of this form of presentation
as well as the lack of specificity of its lesions and the necessity of
ruling out other locations once the fungus is aisolated in the skin.
Diagnosis is simple through skin biopsy and culture. Its important to
determine the cryptococcal antigen. We comment on the current approach
es to treatment during acute and maintenance phases, after the appeara
nce of the new imidazolic compounds such as fluconazole.