CHARGE-REMOTE FRAGMENTATION OF PEPTIDES DERIVATIZED WITH 4-AMINONAPHTHALENESULPHONIC ACID

Authors
LINDH I GRIFFITHS WJ BERGMAN T SJOVALL J
Citation
I. Lindh et al., CHARGE-REMOTE FRAGMENTATION OF PEPTIDES DERIVATIZED WITH 4-AMINONAPHTHALENESULPHONIC ACID, Rapid communications in mass spectrometry, 8(10), 1994, pp. 797-803
Citations number
24
Categorie Soggetti
Spectroscopy,"Chemistry Analytical
Journal title
Rapid communications in mass spectrometry → ACNP
ISSN journal
09514198
Volume
8
Issue
10
Year of publication
1994
Pages
797 - 803
Database
ISI
SICI code
0951-4198(1994)8:10<797:CFOPDW>2.0.ZU;2-5
Abstract
A series of small peptides has been studied by negative-ion fast-atom bombardment mass spectrometry with collision-induced dissociation. It has been found that by derivatizing peptides with 4-aminonaphthalenesu lphonic acid in a peptide linkage at the C-terminus, negative-ion form ation can be enhanced and fragmentation in collision-induced dissociat ion reactions controlled. The peptide-naphthalenesulphonates show char ge-remote fragmentations and the resultant spectra give sequence infor mation.