Dw. Gaines et al., ORNITHINE DECARBOXYLASE, FATTY-ACID SYNTHETASE, AND LIPID-LEVELS IN SELECTED ORGANS OF THE POSTNATAL DEVELOPING MALE MINIATURE PIG, Laboratory animals, 28(4), 1994, pp. 380-386
Ornithine decarboxylase (ODC) and fatty acid synthetase (FAS) activiti
es were determined in tissues from male neonate and juvenile miniature
swine (Hormel-Hanford strain) at various ages. ODC activity was measu
red in liver, brain, kidney, pancreas, and spleen at one day and at 1,
4, 8, 12 and between 24 and 32 weeks. Hepatic FAS activity, total lip
id, triglyceride, and total cholesterol were measured at 2, 8, 16, and
32 weeks. Generally, tissue ODC activity was highest in the spleen at
all ages. Three postnatal patterns of ODC activity were observed for
the different organs. The mean values of FAS activity, total lipid, an
d cholesterol were highest at 8 weeks compared to other sampling perio
ds.