Sa. Lang et al., HEMOGLOBIN-HAMMERSMITH PRECLUDES MONITORING WITH CONVENTIONAL PULSE OXIMETRY, Canadian journal of anaesthesia, 41(10), 1994, pp. 965-968
We report a case of a 15-yr-old North American Indian female with haem
oglobin Hammersmith, scheduled for elective tonsillectomy, whose arter
ial oxygen saturation could not be reliably monitored perioperatively
because of technical limitations of conventional dual wavelength pulse
oximetry. The patient was chronically icteric. She had an atrial sept
al defect with a small L --> R shunt demonstrated by echocardiography.
On arrival in the operating room pulse oximetry (Nellcor-Model N100)
demonstrated a saturation of 45% whilst breathing room air. Her oxygen
saturation increased to 60% whilst breathing 100% oxygen via a face m
ask. An arterial blood gas performed whilst breathing 100% oxygen reve
aled a PaO2 of 418 mmHg. Tonsillectomy was completed uneventfully unde
r general anaesthesia. The pulse oximeter did not provide any clinical
ly useful information throughout the case. In conclusion, conventional
dual wavelength pulse oximeters cannot give an accurate estimate of o
xygenation in patients with haemoglobin Hammersmith. Assessment of oxy
genation in these patients requires alternative monitoring techniques.