Colic is a syndrome of persistent crying in infants, with multiple cau
ses. In most cases, it is within the spectrum of normal variability in
infant behavior and can be treated with reassurance, education, and c
ounseling about appropriate parental responses. In a minority of cases
, careful analysis of the crying pattern and other infant behaviors ma
y suggest an underlying gastrointestinal problem that may be amenable
to more specific treatment. This article explores the evidence support
ing the use of crying and behavioral diaries to determine an appropria
te response to each colicky infant.