Infection with Rhodococcus equi has been described as a cause of cavit
ary pneumonia in AIDS patients. We report such a case, complicated by
bacteremia, tamponade, and possible brain and liver abscesses. Medical
treatment was successful with pericardiocentesis and antibiotherapy w
ith teicoplanin, gentamicin, clarythromycin, rifampicin, supplemented
by empirical treatment of cerebral toxoplasmosis. Antibiotherapy was t
erminated after 6 months, without relapse 2 months later.