SYNTHESIS, CHARACTERIZATION AND ANTIFUNGAL ACTIVITY OF COPPER(II), ZINC(II), COBALT(II) AND NICKEL(II) COMPLEXES DERIVED FROM 2-CHLOROBENZALDEHYDE AND GLYCINE

Copper(II), zinc(II), cobalt(II) and nickel(II) complexes with the Sch iff base derived from 2 - chlorobenzaldehyde and glycine were synthesi zed. These compounds have been characterized by elemental analyses, co nductivity measurements, infra-red and electronic spectra. The Schiff base ligand has been further characterized by H-1 NMR. The results sug gest that the Schiff base acts as a bidentate ligand which bonds to me tal ions through the imino nitrogen and carboxylate oxygen. The Schiff base is a 1 : 1 electrolyte but all the complexes are non-electrolyte s. The results of preliminary tests of antifungal activity of all the compounds show that the complexes strongly inhibit the fungi gypseum, floccosum, canis and rubrum.