EVALUATION OF A 22-KDA DIROFILARIA-IMMITIS ANTIGEN FOR THE IMMUNODIAGNOSIS OF HUMAN PULMONARY DIROFILARIASIS

Authors
PERERA L MURO A CORDERO M VILLAR E SIMON F
Citation
L. Perera et al., EVALUATION OF A 22-KDA DIROFILARIA-IMMITIS ANTIGEN FOR THE IMMUNODIAGNOSIS OF HUMAN PULMONARY DIROFILARIASIS, Tropical medicine and parasitology, 45(3), 1994, pp. 249-252
Citations number
16
Categorie Soggetti
Parasitiology,"Tropical Medicine
Journal title
Tropical medicine and parasitology → ACNP
ISSN journal
01772392
Volume
45
Issue
3
Year of publication
1994
Pages
249 - 252
Database
ISI
SICI code
0177-2392(1994)45:3<249:EOA2DA>2.0.ZU;2-I
Abstract
Human pulmonary dirofilariosis usually appears as a solitary pulmonary nodule. A 22 kDa antigen from Dirofilaria immitis adult worms specifi cally recognized by three sera from individuals diagnosed with pulmona ry dirofilariosis was identified by enzyme-linked-immunoelectrotransfe r blot. This antigen was purified by elution from acrylamide gels and evaluated in enzyme-linked immunoassay using sera from 92 patients wit h pulmonary dirofilariosis and other pulmonary and parasitic diseases. Its use in the diagnosis of human pulmonary dirofilariosis should be considered.