HEAT-SHOCK PROTEIN-PEPTIDE COMPLEXES IN CANCER-IMMUNOTHERAPY

Authors
SRIVASTAVA PK UDONO H
Citation
Pk. Srivastava et H. Udono, HEAT-SHOCK PROTEIN-PEPTIDE COMPLEXES IN CANCER-IMMUNOTHERAPY, Current opinion in immunology, 6(5), 1994, pp. 728-732
Citations number
30
Categorie Soggetti
Immunology
Journal title
Current opinion in immunology → ACNP
ISSN journal
09527915
Volume
6
Issue
5
Year of publication
1994
Pages
728 - 732
Database
ISI
SICI code
0952-7915(1994)6:5<728:HPCIC>2.0.ZU;2-L
Abstract
Heat shock proteins (HSPs) are associated with a broad spectrum of pep tides derived from the cells from which they are isolated. Vaccination with such HSP-peptide complexes elicits protective immunity against t umors or other cells used as the source of HSPs. These observations su ggest that HSP-peptide complexes are suitable as vaccines against canc ers and infectious diseases.