IDENTIFICATION OF THE TRIGGERS OF CELIAC SPRUE

Authors
SALTZMAN JR CLIFFORD BD
Citation
Jr. Saltzman et Bd. Clifford, IDENTIFICATION OF THE TRIGGERS OF CELIAC SPRUE, Nutrition reviews, 52(9), 1994, pp. 317-319
Citations number
7
Categorie Soggetti
Nutrition & Dietetics
Journal title
Nutrition reviews → ACNP
ISSN journal
00296643
Volume
52
Issue
9
Year of publication
1994
Pages
317 - 319
Database
ISI
SICI code
0029-6643(1994)52:9<317:IOTTOC>2.0.ZU;2-D
Abstract
Three theorefically antigenic synthetic peptide subunits of alpha-glia din were evaluated in vivo in four patients with celiac disease. A seq uence of alpha-gliadin (amino acids 31-49) was toxic in all patients, suggesting that this sequence is one of the triggers of the immune sys tem in celiac sprue.