IMMUNOLOGICAL SIGNS OF LICHEN RUBER PLANU S PROGRESS

Immunity status of 106 patients with various forms of lichen ruber pla nus was examined with due consideration for clinical manifestation of the process. Mature T and B cells, cells with T-helper and T-suppresso r phenotype were assessed using monoclonal antibodies. Immunoglobulins were measured by radial immunodiffusion in agar. A correlation betwee n two signs characteristic of the immunity status of patients with lic hen planus was detected: deficiency of T cells with suppressor phenoty pe and increased IgG level, this correlation becoming still more marke d as the process progresses. IgA level is reduced. The immunity status was found not related to disease clinical form.