SANDIMMUN THERAPY OF PATIENTS WITH GRAVE PSORIASIS

Clinicolaboratory study of the effect of sandimmun in grave forms of p soriasis was carried out. A total of 70 psoriasis patients and 40 dono rs were examined. Sandimmun was found to be an effective agent inducin g a rapid remission in cases when routine methods fail. A course of sa ndimmun therapy resulted in clinical cure in 67 patients and in a mark ed improvement in 7. The therapy in selected doses was not as a rule a ssociated with changes in renal or hepatic function or with noticeable shifts in immunity status.