Although attention to novelty is no longer as vital to survival as in
our ancient past, the attention value of novelty has major implication
s for contemporary human communication. It also is affected by individ
ual differences in reactivity to intense and novel stimulation. The st
udies reported in this article involve the roles of attention and sens
ation seeking in responses to drug abuse prevention campaigns in the m
ass media. Early studies have indicated that adolescent high-sensation
seekers are two to seven times more likely to report using drugs-rang
ing from alcohol to cocaine-than lower sensation seekers, identifying
them as prime target audiences for prevention campaigns. This article
describes a series of studies, ranging from laboratory studies on diff
erential effects of messages on high- and low-sensation seekers, and o
n effects of program context, to a field experiment in which high-sens
ation seekers were targeted.