Gw. Brown et al., CLINICAL AND PSYCHOSOCIAL ORIGINS OF CHRONIC DEPRESSIVE EPISODES .2. A PATIENT INQUIRY, British Journal of Psychiatry, 165, 1994, pp. 457-465
Background. We consider how well the psychosocial and clinical factors
found to predict a chronic course for depressive episodes in the comm
unity, held for female psychiatric patients. Method. A consecutive ser
ies of depressed patients, aged 18 to 60, treated as in-patients, out-
patients or day-patients at psychiatric departments of two London hosp
itals, were interviewed initially and at follow-up two years later. Re
sults. indices of childhood adversity and current interpersonal diffic
ulties predicted episodes taking a chronic course (of more than 12 mon
ths' duration). Half of the episodes associated with one or the other
factor were chronic, compared with 22% of those with neither. The pati
ents were at higher risk than the community series (75% v. 34%) and th
is explains their much greater rate of chronicity. There was also some
evidence that social support reduced risk. Clinical features and the
presence of a personality disorder were unrelated to chronicity. Concl
usions. Similar psychosocial factors are important for predicting chro
nicity in both community and patient series.