In recent years the corpus callosum has provided a model for the study
of cortical connections in the adult and developing brain. In particu
lar, aspects of development originally described in the corpus callosu
m could be generalized to other cortical connections. New frontiers in
clude the analysis of the human corpus callosum, studies of callosal c
onnections at the cellular lever and the analysis of dynamic interacti
ons between the hemispheres. Gross morphological parameters of the hum
an corpus callosum have been measured and related to gender, handednes
s etc. The detailed dendritic and axonal morphology of individual call
osal neurons and their development is being defined. Electrophysiologi
cal investigations and computer simulations are stressing temporal asp
ects of the interactions between the hemispheres.