The interhemispheric control of manual motor processes is reviewed, fo
cusing on the clinical evidence from patients with commissurotomies an
d with agenesis of the corpus callosum. There is little evidence for a
role of the corpus callosum in transferring explicit motor commands.
Rather, the corpus callosum seems important for transferring lateralis
ed information (such as verbal or visuospatial activity) of the pre-mo
tor. variety. Also, the corpus callosum may become very significant wh
en movement begins: there appears to be a transcallosal passage of cor
ollary motor signals and feedback sensory signals that are used to con
trol asynchronous bimanual movements and to inhibit the opposite hemis
phere from interfering when a simple unimanual movement is required.