CHEMISTRY OF 1,3-DIMETHYL-1,3-DIAZA-5,6-B ENZO-2-LAMBDA(3)-PHOSPHORANE-4-ONES - REACTIONS WITH HEXAFLUOROACETANE - THERMOLYTIC AND HYDROLYTIC CONVERSION OF THE SPIROPHOSPHORANES FORMED

The reactions of the 1,3-dimethyl-1,3-diaza-2-P-substituted-?? (2-chlo roethyl)- or s(2-chloroethyl)amino-2lambda3-phosphorinan-4-ones 1 and 4 with hexafluoroacetone in a molar ratio of 1:2 furnished the spiroph osphoranes 2 and 5. In the reaction of 1 with hexafluoroacetone, small amounts of the by-product 3, involving lambda4 phosphorus were formed and characterized by F-19 and P-31 NMR spectroscopy. The -1,3-diaza-2 -oxo-5,6-benzo-2lambda4-phosphorinan?? -4-ones 6 and 7 were obtained f rom the spirophosphoranes 2 and 5, either by reaction with water or on heating; in the latter case, the elimination of tetrakis(trifluoromet hyl)oxirane is suggested as occurring. Characterization of 2 and 5-7 w as on the basis of their H-1-, C-13-, F-19-, and P-31--NMR spectra, an d their mass spectra.