SYNTHESIS OF 2-F-ALKYLETHYLAMINES - OPTIM IZED PREPARATION OF 2-F-ALKYLETHYL AZIDES AND THEIR REDUCTION TO AMINES

Citation
H. Trabelsi et al., SYNTHESIS OF 2-F-ALKYLETHYLAMINES - OPTIM IZED PREPARATION OF 2-F-ALKYLETHYL AZIDES AND THEIR REDUCTION TO AMINES, Journal of fluorine chemistry, 69(1), 1994, pp. 115-117
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
ISSN journal
00221139
Volume
69
Issue
1
Year of publication
1994
Pages
115 - 117
Database
ISI
SICI code
0022-1139(1994)69:1<115:SO2-OI>2.0.ZU;2-V
Abstract
2-F-Alkylethylamines are very important intermediates in organic fluor ine chemistry. In this work, it has been demonstrated that it is possi ble to combine the advantages of two techniques, i.e. phase-transfer c atalysis and the use of water as a dispersing medium, in the reduction of 2-F-alkylethyl azides, and hence simplify significantly the synthe sis of such amines from 2-F-alkylethyl iodides.