MICROALBUMIN EXCRETION IN PATIENTS WITH POSITIVE EXERCISE ELECTROCARDIOGRAM TESTS

Thirty-three subjects underwent exercise electrocardiogram testing, 20 had a history of myocardial infarction and 13 were age-matched volunt eers. Exercise electrocardiograms were positive in 15 subjects, negati ve in 12 and anomalous in six. Urinary microalbumin excretion was meas ured at rest, 30 and 60 min after exercise. Urinary microalbumin excre tion was expressed as the albumin-creatinine ratio in mg . mmol-1. In the positive exercise electrocardiogram group median albumin-creatinin e ratio increased from 1.0 mg . mmol-1 (95% CI0.94-1.49) at rest to 2. 0 mg . mmol-1 (95% CI 1.51-3.94) 30 min after exercise, whilst in the negative electrocardiogram group median resting and 30 min post exerci se albumin-creatinine ratio values of 0.85 (95% CI 0.53-1.32) and 1.80 (95% CI 0.63-2.32) mg. mmol-1 respectively were not significantly dif ferent. These results suggest that exercise-induced myocardial ischaem ia is associated with increased urinary microalbumin excretion.