THE REGULATION OF PROCYCLIN EXPRESSION IN TRYPANOSOMA-BRUCEI - MAKINGOR BREAKING THE RULES

The identification of procyclins as stage-specific coot proteins of pr ocyclic forms of Trypanosoma brucei has not only provided a convenient molecular marker ibr the differentiation of bloodstream-form trypanos omes into procyclic forms but has also allowed some important insights into gene regulation in trypanosomes. Here, Adrian Hehl and Isabel Ro diti summarize what has been learnt in the past few yean about the con trol mechanisms that may contribute to the stage-specific expression o f procyclins.