Sfs. Halpin et al., PROSPECTIVE EVALUATION OF CEREBRAL-ANGIOGRAPHY AND COMPUTED-TOMOGRAPHY IN CEREBRAL HEMATOMA, Journal of Neurology, Neurosurgery and Psychiatry, 57(10), 1994, pp. 1180-1186
One hundred and two consecutive patients with cerebral haematoma were
prospectively allocated to one of two groups according to their CT on
admission. Group 1 patients were thought to have a high probability of
an underlying structural lesion and underwent cerebral angiography ac
utely. If normal, this was repeated at three months. Group 2 patients
were thought not to have such a lesion and underwent angiography at th
ree months. Patients older than the mean age of the study population,
and hypertensive patients were much less likely to harbour an aneurysm
or arteriovenous malformation than younger or normotensive patients (
p < 0.01; sensitivity 87.9%, specificity 88.6%). An aneurysm or arteri
ovenous malformation was the cause of haemorrhage in 12.8% of hyperten
sive patients, in 30.9% of patients with haematoma involving the basal
ganglia, and 18.2% of those with posterior fossa haemorrhage. Feature
s of CT in isolation give a sensitivity of 77.2% and a specificity of
84.2%. Follow up angiography in group 1 showed an arteriovenous malfor
mation in one of seven patients in whom the original study was normal.
These results contrast sharply with data from previous retrospective
studies. The decision to investigate a patient with cerebral haematoma
should be primarily based on the patient's clinical condition, rather
than on the site of haemorrhage.