INSTRUMENTAL-CONDITIONING OF FAST (20 TO 50-HZ) OSCILLATIONS IN CORTICOTHALAMIC NETWORKS

Citation
F. Amzica et al., INSTRUMENTAL-CONDITIONING OF FAST (20 TO 50-HZ) OSCILLATIONS IN CORTICOTHALAMIC NETWORKS, Proceedings of the National Academy of Sciences of the United Statesof America, 94(5), 1997, pp. 1985-1989
Citations number
28
Categorie Soggetti
Multidisciplinary Sciences
ISSN journal
00278424
Volume
94
Issue
5
Year of publication
1997
Pages
1985 - 1989
Database
ISI
SICI code
0027-8424(1997)94:5<1985:IOF(T5>2.0.ZU;2-6
Abstract
Cats were instrumentally conditioned to generate grouped fast (20- to 50-Hz) oscillations in motor cortex (area 4). Over seven experimental sessions, there was a spatially selective increased generation of grou ped fast oscillations in that electroencephalogram lead. This locally increased generation of fast oscillations in cortex was associated wit h a widespread increase in synchrony of fast oscillations in thalamoco rtical networks, as demonstrated by crosscorrelations between intracor tical, corticothalamic, and intrathalamic field potentials, A three-se ssion extinction period abolished the local increase in generation of grouped fast oscillations and reset the thalamocortical synchrony of f ast oscillations to control values, A subsequent series of seven sessi ons with instrumental conditioning of fast oscillations in visual cort ex (area 17) reproduced the results from area 4, with a spatially sele ctive increased generation of grouped fast oscillations in the criteri on lead, associated with a widespread increase in thalamocortical sync hrony of fast oscillations, In addition to their presence during the c onditioning sessions, the changes in synchrony of fast oscillations we re expressed during periods of quiet waking, rapid-eye-movement sleep, and nonrapid-eye-movement sleep recorded during the first hour after the end of the conditioning.