PRODUCTION OF A HEMOLYTIC FACTOR BY CANDIDA-ALBICANS

Authors
MANNS JM MOSSER DM BUCKLEY HR
Citation
Jm. Manns et al., PRODUCTION OF A HEMOLYTIC FACTOR BY CANDIDA-ALBICANS, Infection and immunity, 62(11), 1994, pp. 5154-5156
Citations number
19
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
62
Issue
11
Year of publication
1994
Pages
5154 - 5156
Database
ISI
SICI code
0019-9567(1994)62:11<5154:POAHFB>2.0.ZU;2-Y
Abstract
Candida albicans exhibits hemolytic activity when grown on glucose-enr iched blood agar. This activity is present on intact organisms, and it is secreted into the culture medium. Hemoglobin released from lysed e rythrocytes can restore the transferrin-inhibited growth of C. albican s. We conclude that C. albicans expresses a hemolytic factor which all ows it to acquire iron from host erythrocytes.