TRANSIENT CENTRAL HYPOTHYROIDISM AS A CAUSE OF FAILURE-TO-THRIVE IN NEWBORNS AND INFANTS

The course of two neonates and one 4-month-old infant with laboratory and clinical evidence of central hypothyroidism is described. All thre e presented with failure to thrive and improved after L-T-4 therapy. E arly recognition and treatment of newborns and infants with central hy pothyroidism is important to maximize the potential for growth and dev elopment. Two of the three infants have been documented to have transi ent central hypothyroidism of hypothalamic origin, not previously repo rted.