INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR EXPRESSION IN MAMMALIAN OLFACTORY TISSUE

Authors
SMUTZER G ZIMMERMAN JE HAHN CG RUSCHEINSKY DD RODRIGUEZ A HAN LY ARNOLD SE
Citation
G. Smutzer et al., INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR EXPRESSION IN MAMMALIAN OLFACTORY TISSUE, Molecular brain research, 44(2), 1997, pp. 347-354
Citations number
25
Categorie Soggetti
Neurosciences
Journal title
Molecular brain research → ACNP
ISSN journal
0169328X
Volume
44
Issue
2
Year of publication
1997
Pages
347 - 354
Database
ISI
SICI code
0169-328X(1997)44:2<347:I1REIM>2.0.ZU;2-M
Abstract
Two cDNAs encoding inositol 1,4,5-trisphosphate (IP3) receptors were a mplified from rat olfactory tissue, and both exhibited 100% sequence i dentity to the short (Segment II-) variant of type IP3 receptor. Type III IP3 receptor was also expressed in olfactory tissue. The distribut ion of IP3 receptors included the olfactory epithelium, lamina propria , and glandular tissue. These results demonstrate the co-expression of multiple IP3 receptor subtypes in olfactory cells, and suggest multip le functions for IP3 receptors in this tissue.