HYPERINTENSE LESIONS OF THE GLOBUS-PALLIDUS ON MRI IN CHILDREN WITH CHRONIC LIVER-DISEASE

In three children with chronic liver disease of different aetiology wi thout obvious hepatic encephalopathy, bilateral and sym metrical hyper intensity of the globus pallidus in T-1-weighted images was found on c ranial MRI. Reversibility was shown in one child with autoimmune hepat itis after normalisation of liver function tests under immunosuppressi ve therapy. Conclusion As central nervous system involvement in liver disease is only partially understood, brain imaging by MRI offers a po tential additional tool to further elucidate the incidence and time co urse of previously undetected brain alterations.