A. Ballauff et al., HYPERINTENSE LESIONS OF THE GLOBUS-PALLIDUS ON MRI IN CHILDREN WITH CHRONIC LIVER-DISEASE, European journal of pediatrics, 153(11), 1994, pp. 802-806
In three children with chronic liver disease of different aetiology wi
thout obvious hepatic encephalopathy, bilateral and sym metrical hyper
intensity of the globus pallidus in T-1-weighted images was found on c
ranial MRI. Reversibility was shown in one child with autoimmune hepat
itis after normalisation of liver function tests under immunosuppressi
ve therapy. Conclusion As central nervous system involvement in liver
disease is only partially understood, brain imaging by MRI offers a po
tential additional tool to further elucidate the incidence and time co
urse of previously undetected brain alterations.