ISOLATION OF A NEW H3.3 HISTONE VARIANT CDNA OF P-LIVIDUS SEA-URCHIN - SEQUENCE AND EMBRYONIC EXPRESSION

Citation
L. Fucci et al., ISOLATION OF A NEW H3.3 HISTONE VARIANT CDNA OF P-LIVIDUS SEA-URCHIN - SEQUENCE AND EMBRYONIC EXPRESSION, Biochimica et biophysica acta, N. Gene structure and expression, 1219(2), 1994, pp. 539-542
Citations number
22
Categorie Soggetti
Biology,Biophysics
ISSN journal
01674781
Volume
1219
Issue
2
Year of publication
1994
Pages
539 - 542
Database
ISI
SICI code
0167-4781(1994)1219:2<539:IOANHH>2.0.ZU;2-X
Abstract
A cDNA encoding a new H3 histone variant has been isolated from a Para centrotus lividus sea urchin embryo cDNA library. The encoded protein is identical to the H3.3 histone subtype identified in other species, with the difference that E replaces D at position 81. The clone corres ponds to a transcript of about 1.6 kb, not dependent on DNA replicatio n, present in the unfertilized egg and at all stages of embryonic deve lopment. The coding part of the cDNA cross-reacts also with a 0.5 kb H 3 late histone mRNA.