L. Fucci et al., ISOLATION OF A NEW H3.3 HISTONE VARIANT CDNA OF P-LIVIDUS SEA-URCHIN - SEQUENCE AND EMBRYONIC EXPRESSION, Biochimica et biophysica acta, N. Gene structure and expression, 1219(2), 1994, pp. 539-542
A cDNA encoding a new H3 histone variant has been isolated from a Para
centrotus lividus sea urchin embryo cDNA library. The encoded protein
is identical to the H3.3 histone subtype identified in other species,
with the difference that E replaces D at position 81. The clone corres
ponds to a transcript of about 1.6 kb, not dependent on DNA replicatio
n, present in the unfertilized egg and at all stages of embryonic deve
lopment. The coding part of the cDNA cross-reacts also with a 0.5 kb H
3 late histone mRNA.