ORONASAL LEISHMANIASIS CAUSED BY A PARASITE WITH AN UNUSUAL ISOENZYMEPROFILE

A 45-year-old Sudanese man from western Sudan presented with oronasal leishmaniasis of three years duration. He had no history of previous k ala-azar or cutaneous leishmaniasis, The parasite isolated from the or al mucosa was characterized by isoenzymes using 12 enzymes and by poly merase chain reaction amplification of kinetoplast DNA using species-s pecific primers. The specific primers gave products indistinguishable from those of the Leishmania donovani complex. However, the isoenzyme profile showed a zymodeme pattern that was significantly different fro m the zymodemes peviously reported in the Sudan and the Ethiopian regi on.