Measuring symptom specific health outcome is complex, but the methodol
ogies now exist to develop measures with the appropriate properties. A
s one element of a major programme to develop multidomain health outco
me measures for chronic disease, a symptom based measure for asthma ca
re has been developed for use in general practice and outpatient depar
tments. This article outlines the development process, which used a fr
amework recently described in the theoretical literature to show the c
onstraints that scientific criteria place on the development of outcom
e measures and the means of overcoming such limiting factors. Although
substantial effort is required to undertake a rigorous process of dev
elopment, useful tools are the result. Two five item, symptom based ou
tcome measures for adult asthma are described.