Pulse oximetry has been advocated as a simple non-invasive investigati
on of vascular compromise. Its usefulness in aiding diagnosis of micro
vascular compromise in a developing compartment syndrome is questioned
. This study investigates the reproducibility of pulse oximetry and th
e effect on arterial haemoglobin saturation of raising limb intracompa
rtmental pressure by compression bandaging. In 32 out of 50 normal sub
jects there was a difference in percentage saturation between right an
d left arms, with a 2% difference in 6 people (12%). Percentage satura
tion fell significantly at average bandage pressures of 80 mmHg (P < 0
,0001) and 60 mmHg (P < 0,001). At clinically relevant pressures, the
test had a sensitivity of 40,4%. With a greater than 50% risk of a fal
se-negative result, pulse oximetry is not an appropriate additional in
vestigation in the detection of raised intra-compartmental pressure.