CIRRHOSIS IN PATIENTS WITH RHEUMATOID-ARTHRITIS RECEIVING LOW-DOSE METHOTREXATE

Authors
CHANDRAN G AHERN MJ HALL PDM GEDDES R SMITH MD HILL W HARLEY JH
Citation
G. Chandran et al., CIRRHOSIS IN PATIENTS WITH RHEUMATOID-ARTHRITIS RECEIVING LOW-DOSE METHOTREXATE, British journal of rheumatology, 33(10), 1994, pp. 981-984
Citations number
18
Categorie Soggetti
Rheumatology
Journal title
British journal of rheumatology → ACNP
ISSN journal
02637103
Volume
33
Issue
10
Year of publication
1994
Pages
981 - 984
Database
ISI
SICI code
0263-7103(1994)33:10<981:CIPWRR>2.0.ZU;2-6
Abstract
We describe three patients with RA who developed cirrhosis while takin g low dose methotrexate (MTX). This report includes a review of the ri sk factors for cirrhosis occurring in association with MTX. Two of the se patients were part of a prospective study to quantify changes in pe ricellular and total collagen in 76 patients with RA receiving low dos e pulse MTX, giving a point prevalence of cirrhosis of 2.63%.