A female Japanese black calf suffering from diarrhoea was treated with
six different antibiotics for 9 days. The diarrhoea worsened and the
calf was killed when 17 days old. At necropsy, the mucosal surface of
the forestomachs showed diffuse haemorrhagic necrosis and pseudomembra
ne formation. Candida glabrata infection was diagnosed histologically,
immunohistochemically, and by isolation and examination of the yeast.
The intensive antibiotic treatment was considered to have been a pred
isposing or exacerbating factor. This is the first report of C. glabra
ta infection of the bovine forestomachs.