K. Huml et B. Kratochvil, ROLE OF X-RAY CRYSTALLOGRAPHY FOR PHARMAC EUTICAL RESEARCH, DEVELOPMENT AND MANUFACTURE, Chemicke listy, 88(10), 1994, pp. 628-635
This review article describes applications of X-ray diffraction method
s in pharmaceutical research, development and drug industry. The influ
ence of crystal habit and internal structure (crystalline, amorphous)
on drug properties and technology is mentioned. Crystallographic datab
ases and the role of X-ray structure studies in drug design are also i
ncluded.