SYNTHESIS AND CONFORMATIONAL STUDIES OF B RANCHED OLIGOSACCHARIDES .15. 2,3-DI-O-GLYCOSYLATED METHYL ALPHA-L-RHAMNOPYRANOSIDES CONTAINING 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSYL RESIDUES

Authors
NIFANTEV NE SHASHKOV AS KHATUNTSEVA EA TSVETKOV YE SHERMAN AA KOCHETKOV NK
Citation
Ne. Nifantev et al., SYNTHESIS AND CONFORMATIONAL STUDIES OF B RANCHED OLIGOSACCHARIDES .15. 2,3-DI-O-GLYCOSYLATED METHYL ALPHA-L-RHAMNOPYRANOSIDES CONTAINING 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSYL RESIDUES, Bioorganiceskaa himia, 20(8-9), 1994, pp. 1001-1012
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Bioorganiceskaa himia → ACNP
ISSN journal
01323423
Volume
20
Issue
8-9
Year of publication
1994
Pages
1001 - 1012
Database
ISI
SICI code
0132-3423(1994)20:8-9<1001:SACSOB>2.0.ZU;2-B
Abstract
A series of methyl 2,3-di-O-glycosyl-alpha-L-rhamnopyranosides with 2- acetamido-2-deoxy-beta-D-glucopyranosyl substituents have been synthes ized and the deviations from additivity (DELTADELTA) in their C-13-NMR spectra determined. It is shown that the DELTADELTA values for the tr isaccharides with the GlcNAc substituent at O-2 of the diglycosylated Rha may markedly differ from the DELTADELTA values in the spectra of t he respective trisaccharides with the Glc substituent. These deviation s are probably associated with the intramolecular spatial interactions with participation of the NHAc-group.