O. Nativ et al., THE MALIGNANT POTENTIAL OF POSTCHEMOTHERAPY RESIDUAL MATURE TERATOMA FOR DISSEMINATED NONSEMINOMATOUS TESTICULAR-TUMORS, European urology, 26(3), 1994, pp. 216-218
Flow cytometric nuclear DNA ploidy analysis was used to study 7 paraff
in-embedded tissue blocks from 3 patients with postchemotherapy residu
al mature teratomas. All specimens contained abnormal DNA and were cla
ssified as DNA aneuploid. These findings indicate that despite the ben
ign appearance of postchemotherapy mature teratomas, these lesions are
susceptible to resume malignant behavior. Therefore, complete surgica
l removal is recommended.