Objective: To analyze the actual cost of pediatric intensive care and
its different components, particularly the differences between various
patient groups, with special reference to the variable cost and the e
lements included in it. Design: Prospective, observational study. Sett
ing: Multidisciplinary 12-bed pediatric intensive care unit (PICU) in
a tertiary university hospital. Patients: 495 admissions to the unit o
ver 17 consecutive months; 64.2 % were medical patients and 35.8 % wer
e surgical patients; the mean (SE) stay in the PICU was 6.6 +/- 0.3 da
ys. Measurements and results: The fixed cost per day per patient was c
alculated, including the costs of physicians, nurses, auxiliary and ot
her personnel who worked during the study period, and the costs of str
uctural depreciation, maintenance, consumption, and disposable materia
l. The variable cost was individually calculated from the costs of rou
tine procedures and also included expenditure on pharmaceuticals, bloo
d products, biochemical, hematological, and bacteriologic tests, radio
logy, image diagnosis procedures, and other procedures. The Physiologi
c Stability Index (PSI) was obtained in the first 24 h after admission
. The mean fixed cost per patient per day was u. s. $ 608, which repre
sents 72 % of the total patient cost during this study; 86 % of this a
mount was for personnel (58 % for nurses and auxiliary staff). Variabl
e costs came to 28 % of the total amount, and were $ 218 +/- 100 (M +/
- SEM) per patient per day. In addition to the costs of their longer s
tay in the PICU, the daily variable costs of nonsurvivors were higher
than those of survivors ($ 542 +/- 52 vs $ 179 +/- 7; p < 0.001). We c
lassified the patients into four groups according to their PSI score i
n the first 24 h; variable daily costs increased (p < 0.05) in all com
parisons with the PSI level: group I: < 4 points ($ 155 +/- 0.5), grou
p II: 5-9 points ($ 210 +/- 13), group III: 10-14 points ($ 324 +/- 54
), group IV: > 15 points ($ 480 +/- 42). However, this pattern was not
found for all resources: the cost of treatment techniques and biochem
ical and hematological tests increased, but the consumption of antibio
tics, parenteral nutrition, blood products, and bacteriologic tests re
ached their maximum level in groups I-III and radiology was not signif
icantly influenced by PSI level. Conclusions: The cost of personnel wa
s the biggest factor in intensive care costs: 62.4 % of the total cost
s. Nonsurvivors generated 3 times the mean variable daily expenditure
on survivors and had longer stays in the PICU. The increase in PSI sco
re on the first day was associated with a global increase in variable
costs. The cost of treatment techniques significantly increased as the
illness became more severe but consumption of antibiotics and parente
ral nutrition and use of bacteriologic tests and radiology did not.