SYNTHESIS OF OPTICALLY-ACTIVE ALPHA-HYDROXY LACTONES BY SHARPLESS ASYMMETRIC DIHYDROXYLATIONS OF KETENE ACETALS, ENOL ETHERS, AND ENE LACTONES

Authors
CURRAN DP KO SB
Citation
Dp. Curran et Sb. Ko, SYNTHESIS OF OPTICALLY-ACTIVE ALPHA-HYDROXY LACTONES BY SHARPLESS ASYMMETRIC DIHYDROXYLATIONS OF KETENE ACETALS, ENOL ETHERS, AND ENE LACTONES, Journal of organic chemistry, 59(21), 1994, pp. 6139-6141
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
59
Issue
21
Year of publication
1994
Pages
6139 - 6141
Database
ISI
SICI code
0022-3263(1994)59:21<6139:SOOALB>2.0.ZU;2-X
Abstract
Three different AD routes to optically active alpha-hydroxy lactones o f good to excellent optical purity are reported. The substrates for th e AD reaction are endocyclic ketene acetals, endocyclic enol ethers, a nd exocyclic alpha,beta-unsaturated lactones.