ASYMMETRIC ALLYLATION OF AROMATIC-ALDEHYDES CATALYZED BY CHIRAL PHOSPHORAMIDES PREPARED FROM (S)-PROLINE

Authors
ISEKI K KUROKI Y TAKAHASHI M KISHIMOTO S KOBAYASHI Y
Citation
K. Iseki et al., ASYMMETRIC ALLYLATION OF AROMATIC-ALDEHYDES CATALYZED BY CHIRAL PHOSPHORAMIDES PREPARED FROM (S)-PROLINE, Tetrahedron, 53(10), 1997, pp. 3513-3526
Citations number
41
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
10
Year of publication
1997
Pages
3513 - 3526
Database
ISI
SICI code
0040-4020(1997)53:10<3513:AAOACB>2.0.ZU;2-R
Abstract
Chiral phosphoramides prepared from (S)-proline were used to catalyze the allylation and crotylation of aromatic aldehydes with allylic tric hlorosilanes in good enantioselective yields. Phosphoramides 4d and 4m gave chiral homoallylic alcohols and their enantiomers, respectively, with similar levels of enantioselectivity. (C) 1997 Elsevier Science Ltd.