Dl. Pelletier et al., A METHODOLOGY FOR ESTIMATING THE CONTRIBUTION OF MALNUTRITION TO CHILD-MORTALITY IN DEVELOPING-COUNTRIES, The Journal of nutrition, 124(10), 1994, pp. 190002106-190002122
According to conventional methods of classifying cause of death, appro
ximately 70% of child deaths (0-4 y) worldwide are due to a small numb
er of priority infectious diseases which, in turn, receive the vast ma
jority of donor and national resources in the health sector, Despite t
he long-recognized synergism between malnutrition and infection in the
causation of child mortality, malnutrition does not appear as a major
cause of death in health statistics from developing countries. Part o
f the reason for this has been the difficulty of estimating the percen
t of deaths due to malnutrition, because the conventional methods of c
lassifying cause of death do not recognize the potentiating effect of
malnutrition on the disease. The purpose of this paper is to develop a
nd test a simple methodology to estimate the percent of child deaths i
n a given country or community that is due to malnutrition's potentiat
ing effects on prevailing infectious diseases. The cornerstone of the
methodology is knowledge of the strength of the association between ma
lnutrition and mortality in developing countries, as measured in eight
prospective studies. These studies reveal remarkable consistency in r
elative risk across different grades of malnutrition. The mean and SE
of relative risk for severe malnutrition is 8.4 +/- 2.1, for moderate
malnutrition it is 4.6 +/- 0.9, and for mild malnutrition it is 2.5 +/
- 0.3. When applied to survey data from Ethiopia, Malawi, Guatemala an
d India for illustrative purposes, this methodology indicates that 42-
57% of all child deaths in these samples (6-59 mo) ace due to malnutri
tion's potentiating effects on infectious disease, of which 76-89% is
attributable to mild-to-moderate malnutrition. This methodology is rec
ommended for use in a variety of policy and planning applications.