Objective: To assess the cost of the mandatory use of high-efficiency
particulate respirators to treat patients with known or suspected tube
rculosis. Design: A questionnaire was used to determine the number of
high-efficiency particulate respirators required and the number of cas
es of tuberculosis in employees that could potentially be prevented. I
ndirect costs included the training and fitness testing of employees.
The clinical efficacy of respirators is not known, To provide a best-c
ase scenario, it was assumed that the respirators could prevent as man
y as 25% of tuberculosis cases in health care workers. Setting: 159 ac
ute care facilities administered by the Department of Veterans Affairs
. Participants: Quality improvement, infection control, and employee h
ealth specialists. Measurements: Cost of the respirators compared with
their maximum predicted efficacy. Results: The use of the respirators
would cost $7 million per case of tuberculosis prevented and $100 mil
lion per life saved. Conclusions: High-efficiency particulate respirat
ors are a costly means of trying to prevent tuberculosis. Costs could
be reduced by reusing masks or by restricting the number of health car
e workers allowed to have contact with potentially infectious patients
. As the health care budget undergoes further restrictions, specific m
eans of accommodating the cost of new regulations must be found.