P. Lagrange et al., FREQUENCY OF ANGIOGRAPHIC RESTENOSIS AT 6 MONTHS AND LONG-TERM OUTCOME AFTER CORONARY ANGIOPLASTY, Archives des maladies du coeur et des vaisseaux, 87(9), 1994, pp. 1161-1167
Five hundred patients with a mean age of 59 years were followed up for
an average of 32 months after coronary angioplasty. All patients were
included in a prospective study comprising coronary angiography at 6
months for 379 patients (91 % primary successes). The long-term outcom
e was evaluated by a questionnaire or telephone interview in all cases
. The global primary success rate was 84.4 % in this series. The prima
ry failures include 1.8 fatalities, 0.6 % myocardial infarction, 2 % e
mergency coronary bypass surgery and 11.2 % without immediate clinical
consequences. At 6 months, there were 48 % of restenoses (182/379 pat
ients) and 28 % underwent immediate repeat angioplasty (141/500 patien
ts) with a primary success rate of 91 %. After the repeat angioplasty,
the restenosis rate was 43 % but this varied according to the time fr
om the first restenosis: 60 % when the interval was short (under 2 mon
ths) compared with 21 % when the interval was 6 months (p < 0.01). The
actuarial survival rates at 4 years were 95 % after successful angiop
lasty 96 % after uncomplicated failures or medically treated restenosi
s and 98 % after bypass surgery. The predictive factors for secondary
death were age of over 70 years, previous non-thrombolysed myocardial
infarction and complications of angioplasty. The long-term outcome was
good despite the 48 % 6 months restenosis rate requiring revascularis
ation procedure in 73 % of cases.