A paraneoplastic alopecia associated with internal malignancy is repor
ted in four cats. Acute, bilaterally symmetrical, ventral glistening a
lopecia, weight loss and lethargy were present in all cats. Skin biops
y specimens exhibited severe follicular and adnexal atrophy with folli
cular miniaturization, minimal inflammation and, in many cases, absenc
e of stratum corneum. At the time of diagnosis, three cats had a metas
tatic pancreatic adenocarcinoma and one had a bile duct carcinoma. Thi
s report confirms, and expands upon the previous report of a syndrome
associating ventral alopecia and metastatic visceral carcinomas in cat
s.