An 11-year-old Doberman Pinscher with clinical and histological skin f
eatures consistent with colour dilution alopecia had a long history of
skin disease. The animal had hundreds of papules affecting the 'blue'
haired areas of the hair coat. The predominant skin lesions included
keratinizing infundibular cysts, keratin horns, perifollicular dermati
tis, and sebaceous hyperplasia; these lesions were often accompanied b
y furunculosis and suppurative panniculitis. Over a 8-month period, 32
lesions were examined histologically, which included two lipomas, one
infiltrative lipoma, one squamous papilloma, two mast cell tumours, f
our cavernous haemangiomas, one haemangiosarcoma, and three melanomas.
It is unknown at present whether the colour dilution phenotype confer
s increased risk for tumours of the skin and or subcutaneous tissues.