Sl. Goldberg et al., BENEFIT OF INTRACORONARY ULTRASOUND IN THE DEPLOYMENT OF PALMAZ-SCHATZ STENTS, Journal of the American College of Cardiology, 24(4), 1994, pp. 996-1003
Objectives. This study was designed to evaluate the changes in intrast
ent and angiographic dimensions when intravascular ul trasound imaging
is used to direct the deployment of balloon-expandable Palmaz-Schatz
stents in coronary arteries and saphenous vein grafts. Background. Int
ravascular ultrasound provides more information than angiography in th
e imaging of intravascular structures. Previous studies have shown tha
t obtaining a larger lumen (greater ''acute gain'') with coronary inte
rventions such as stenting leads to less restenosis and subacute throm
bosis. It is not clear whether the information obtained by intravascul
ar ultrasound can be used to obtain a greater acute gain in lumen dime
nsions. Methods. Forty consecutive patients undergoing Palmaz-Schatz s
tent implantation had intravascular ultrasound imaging performed after
a good angiographic appearance was obtained. If the stent did not app
ear adequately expanded by intravascular ultra sound, or if the struts
were poorly apposed to the arterial wall, further stent dilation with
larger balloons or higher pressure inflations were performed. Twenty
nine patients had subsequent intravascular ultrasound imaging. Intrast
ent diameters and areas were compared from the initial to the final in
travascular ultra sound studies. Results. Of the 40 patients studied,
only 5 (13%) had an adequate result by intravascular ultrasound despit
e an acceptable angiographic appearance in all patients. Six additiona
l patients did not undergo subsequent intravascular ultrasound imaging
. The other 29 patients all demonstrated a significant increase in int
rastent minimal diameter (mean 19%), major diameter (11%) and cross-se
ctional area (34%) (p < 0.001 for all measurements). Conclusions. The
use of intravascular ultrasound imaging in the deployment of balloon e
xpandable Palmaz-Schatz stents leads to a significant increase in intr
astent dimensions (greater ''acute gain'').