EFFECT OF BENDAZAC LYSINE ON LENS AND RETINA IN DIABETICS

The possible beneficial effects on the lens and retina which Bendazac Lysine may have in the treatment of adult diabetic patients were inves tigated. Twenty patients, ranging in age from 54.80 +/- 5.86 years old , were studied. The average duration of the diabetes was 11.32 +/- 4.1 0 years. Thirteen patients had background retinopathy. The metabolic c ontrols carried out during the study were satisfactory (HbA1<11%). Ben dazac Lysine (500 mg three times a day) was administered for 6 months. Blood-retinal barrier permeability (VPR and VPRt) and lens transmitta nce; (t) were evaluated prior to and 6 months after treatment by fluor ophotometry. No statistically significant differences between the pre- and post-treatment values of the retina permeability were observed, h owever, there was a statistically significant improvement (p<0.05) (in itial value: t=0.813 +/- 0.040 and final value: t=0.823 +/- 0.037) in the lens transmittance. The authors conclude that Bendazac Lysine has a beneficial effect on the lens in the diabetic adult although no impr ovement in the permeability of the blood-retinal barrier has been obse rved.