OXYTOCIN ENHANCES, AND OXYTOCIN ANTAGONISM DECREASES, SEXUAL RECEPTIVITY IN INTACT FEMALE RATS

Authors
BENELLI A POGGIOLI R LUPPI P RUINI L BERTOLINI A ARLETTI R
Citation
A. Benelli et al., OXYTOCIN ENHANCES, AND OXYTOCIN ANTAGONISM DECREASES, SEXUAL RECEPTIVITY IN INTACT FEMALE RATS, Neuropeptides, 27(4), 1994, pp. 245-250
Citations number
40
Categorie Soggetti
Neurosciences,"Endocrynology & Metabolism
Journal title
Neuropeptides → ACNP
ISSN journal
01434179
Volume
27
Issue
4
Year of publication
1994
Pages
245 - 250
Database
ISI
SICI code
0143-4179(1994)27:4<245:OEAOAD>2.0.ZU;2-K
Abstract
In intact, non-ovariectomized female rats in spontaneous behavioral es trus, the i.c.v. injection of oxytocin significantly increased lordosi s quotient and lordosis duration, starting from a dose of 1 ng/rat. On the other hand, the oxytocin antagonist, d(CH2)(5)Tyr(Me)-[Orn](8)-va sotocin, injected at the same doses and by the same route, decreased l ordosis quotient and lordosis duration, and prevented the effect of ox ytocin. These data further support the notion that oxytocin plays a ph ysiological role in female sexual receptivity.