STERIC AND ELECTRONIC EFFECTS IN ARENE FORMYLATIONS INVOLVING PYROPHOSPHORYL CHLORIDE

Authors
PANSARE SV RAVI RG
Citation
Sv. Pansare et Rg. Ravi, STERIC AND ELECTRONIC EFFECTS IN ARENE FORMYLATIONS INVOLVING PYROPHOSPHORYL CHLORIDE, Synlett, (10), 1994, pp. 823-824
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
10
Year of publication
1994
Pages
823 - 824
Database
ISI
SICI code
0936-5214(1994):10<823:SAEEIA>2.0.ZU;2-E
Abstract
The regiochemistry of formylation of several activated naphthalenes an d benzenes with pyrophosphoryl chloride and N, N-disubstituted formami des is governed by steric demands of the formylating species and the s ubstrate, but electronic factors may dominate in some cases. Increasin g the size of the formamide in the formylating reagent is beneficial f or controlling regioselectivity.