STRUCTURE OF THE MURINE INTERFERON-ALPHA BETA RECEPTOR-ENCODING GENE - HIGH-FREQUENCY REARRANGEMENTS IN THE INTERFERON-RESISTANT L1210 CELL-LINE/

Authors
LUTFALLA G UZE G
Citation
G. Lutfalla et G. Uze, STRUCTURE OF THE MURINE INTERFERON-ALPHA BETA RECEPTOR-ENCODING GENE - HIGH-FREQUENCY REARRANGEMENTS IN THE INTERFERON-RESISTANT L1210 CELL-LINE/, Gene, 148(2), 1994, pp. 343-346
Citations number
20
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
148
Issue
2
Year of publication
1994
Pages
343 - 346
Database
ISI
SICI code
0378-1119(1994)148:2<343:SOTMIB>2.0.ZU;2-6
Abstract
The structure of the murine IFNAR gene, encoding the interferon alpha/ beta receptor, is reported. The gene has eleven exons dispersed in abo ut 23 kb of genomic DNA. The nature of the rearrangements affecting th is gene in interferon-resistant (IFNR) L1210 mutant cell lines is desc ribed.