PURPOSE: To report the association between amplitude of accommodation
and refractive error. METHODS: Refractive error and amplitudes of acco
mmodation were measured in 1,148 eyes of 696 patients as part of the E
arly Treatment Diabetic Retinopathy Study, RESULTS: Eyes with myopia,
defined as these with a refractive error of -0.75 diopter or more, hav
e lower accommodative amplitudes (P = .005). After multivariate logist
ic regression analysis adjusting for age, occupation, and white race,
lower amplitudes of accommodation remained associated with myopia (P =
.03). CONCLUSIONS: Eyes with lower amplitudes of accommodation must u
se more of their accommodative reserve for near work. Myopia may be an
adaptation that develops in eyes with reduced accommodative amplitude
s.